Justin Trudeau is guilty of criminal negligence for quarantining suspected COVID-19 infected persons in motels and hotels

Throughout Germany and the WHO’s COVID-19 biological warfare attack Justin Trudeau intentionally put the lives and safety of Canadians at risks by mandating suspected COVID-19 infected travelers self-isolate/quarantine themselves in motels and hotels across Canada. Motels and hotels are public places, not health care facilities. Justin Trudeau showed wanton and reckless disregard for the lives or safety of Canadians. According to Canada’s criminal code Justin Trudeau is guilty of criminal negligence

Criminal negligence

  •  (1) Every one is criminally negligent who

    • (a) in doing anything, or

    • (b) in omitting to do anything that it is his duty to do,

    shows wanton or reckless disregard for the lives or safety of other persons.

Canadians couldn’t travel abroad during COVID-19 yet Justin Trudeau brought in hundreds of students from China (origin of the SARS-CoV-2 outbreak) and housed them in motels and hotels across Canada. All of the students were suspected of being infected with COVID-19 when they arrived at various ports of entry. Some were sick when they arrived. Because the Trudeau government suspected they were infected with COVID-19 they were isolated/quarantined in motels and hotels, not in hospitals or quarantine facilities.

Isolation and quarantine are public health measures used to control the spread of contagious disease:

    • Isolation is used to separate and restrict the movement of those who are ill with a communicable disease.
    • Quarantine is used to separate and restrict the movement of those who are still well but who may have been exposed to a communicable disease.

The purpose of quarantine is clearly to prevent additional spread of contagious disease or environmental toxins within a specific population. Quarantining in motels and hotels defeats the purpose of quarantine. Quarantining in motels and hotels facilitates the spread of contagious disease within a specific population. Doing so “shows wanton or reckless disregard for the lives or safety of other persons”

Government and police forensic labs can prove Germany’s mRNA vaccines are biological weapon by looking for SARS-COV-2’s viral protein ORF10

“the term “biological agent” means any microorganism (including, but not limited to, bacteria, viruses, fungi, rickettsiae or protozoa), or infectious substance, or any naturally occurring, bioengineered or synthesized component of any such microorganism or infectious substance, capable of causing— (A) death, disease, or other biological malfunction in a human” US Code 18 USC § 178(1)

Germany’s mRNA vaccines contain 2 bioengineered or synthesized components of SARS-CoV-2. Germany’s vaccines contain SARS-CoV-2’s spike protein (a modified form) and the viral protein that made SARS-COV-2 a novel coronavirus, ORF10.

It’s well known that Germany’s mRNA vaccines are made to instruct a body’s cells to make SARS-CoV-2’s spike protein:

The WHO, CDC, Health Canada and Germany would have you believe that Germany’s vaccines instructing cells to make SARS-CoV-2’s spike protein is harmless yet they all know SARS-CoV-2 needs the spike protein to invade cells to replicate and make you sick.

The WHO, CDC and other health authorities know and have repeatedly stated:

“the novel coronavirus uses spike protein like a key to gain entry to our cells; once inside, the virus is free to replicate, making us sick. The spike protein binds to a protein on the surface of our cells called ACE2, triggering uptake of the virus particle and eventually membrane fusion.”

SARS-CoV-2 can’t invade cells and make us sick without spike (S) protein. Germany’s Pfizer-BioNTech vaccines, in every practical sense, were made to facilitate SARS-CoV-2 infections.

Furthermore,

mRNAs are created as an exact copy (a clone) of the segment of DNA found along the genome corresponding to a protein-coding gene.

UMass Medical School

“Specifically, the Pfizer-BioNTech COVID-19 vaccine is a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine. The lipid coating of the nanoparticles binds to the cell membrane, facilitating entry of the (SARS-CoV-2) mRNA (genetic material) segment into the cell.” AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE (ASRM).

Germany’s COVID-19 mRNA vaccines also contain SARS-CoV-2’s unique viral protein, ORF10. This mRNA vaccine ingredient is intentionally suppressed (to keep from appearing or being known, published) because including SARS-CoV-2’s unique viral protein ORF10 in a vaccine makes Germany’s mRNA vaccine a biological weapon. How?

“Consistent with our observations, in the context of SARS-CoV-2 infection, ORF10 inhibited MAVS expression and facilitated viral replication. In brief, our results reveal a novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.” …

ORF10 plays a vital role at all stages of SARS-CoV-2 infection. In our study, overexpression of ORF10 promoted the degradation of MAVS and the replication of SARS-CoV-2.”

Source : immunology study SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy

Government and police forensic labs in Canada, the USA, the UK and other COVID-19 mRNA vaccine infected states have the means to prove Germany’s mRNA vaccines are biological weapons. Look for the presence of SARS-CoV-2’s viral protein ORF10 in Germany manufactured mRNA vaccines.

SARS-CoV-2’s unique viral protein ORF10 (a biological agent – a bioengineered or synthesized component of SARS-CoV-2) can’t invade cells and make us sick without the spike (S) protein. Germany manufacturing mRNA vaccines that teach cells to make spike protein give SARS-CoV-2’s viral protein ORF10 the “key to gain entry to our cells; once inside, the virus is free to replicate, making us sick”.

“Biological weapons use microbiological agents (such as bacteria, viruses or fungi) or toxins to intentionally cause death or harm to humans, animals, or plants.” Government of Canada

Testing Germany’s mRNA vaccines for the presence of SARS-CoV-2’s disease causing viral protein ORF10 will prove they’re biological weapons. Viral protein ORF10 was intentionally added because “ORF10 plays a vital role at all stages of SARS-CoV-2 infection.” X. Li et al

 

SARS-CoV-2 genetically engineered for the WHO to be a biological weapon

Since 1972 the WHO (the UN) called for/recommended virologists develop the means to prolong virus/coronavirus infections by impairing immune response to a virus:

The below screenshot was taken from the Bulletin of the World Health Organization, Volume 47, p.259, 1972, Recommendations (3)


Virologists prolonged virus/coronavirus infections for the WHO by genetically engineering/modifying the SARS coronavirus in 2003. The human herpes virus protein ORF10 was encoded into the SARS coronavirus to make the novel SARS-CoV-2 – created in 2003 patent US-2006257852-A1

The patent was abandoned because the WHO intended on using it as a biological weapon. AIDS was caused by the WHO using smallpox vaccines made with the live viral component of the infectious and deadly vaccinia virus.

AIDS is now treatable so the WHO needed a new virus to make $billions in treating, not curing, the novel disease. The  herpes virus ORF10 protein was intentionally encoded in SARS to cause and prolong SARS-CoV-2 infections.

“These results indicate that ORF10like its HSV-1 homolog VP16, is a transactivating protein despite the absence of sequences similar to the VP16 carboxy-terminal domain. The transactivating function of the ORF10 tegument protein may be critical for efficient initiation of viral infection” 1993 Journal of Virology published study

In the context of gene regulation: transactivation is the increased rate of gene expression triggered either by biological processes or by artificial means, through the expression of an intermediate transactivator protein. HIV, HTLV and 2003 patented SARS-CoV-2 are three of the many viruses that encode transactivating proteins (e.g. ORF10) to enhance viral gene expression.

“Viral mRNA can efficiently hijack host ribosomes during infection for translation of proteins necessary for virus propagation. Initiation of translation is a key step, during which the coding region of mRNA, open reading frame (ORF), gets properly positioned on the ribosome.” UMass Medical School

“Nuclear export of host mRNAs is critical for proper cellular functions and survival. To mitigate this effort, viruses have evolved multiple strategies to inhibit this process. Distinct to the generally nonselective inhibition mechanisms, ORF10 from gammaherpesviruses blocks nuclear export of selective mRNAs by forming a complex with Rae1 (RNA export 1) and Nup98 (nucleoporin 98).” October 8, 2020 published research article – Molecular mechanism  underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10

Millions intentionally misdiagnosed as having COVID-19 to assist Germany and the UN obtain $billions by waging COVID-19 biological warfare

Millions have been intentionally misdiagnosed as testing positive for COVID-19 in Canada, the US, the UK, in Europe and around the World to assist Germany and the WHO further UN’s global vaccine agenda and obtain $billions under false pretence. There is ample evidence to support charging Germany and the WHO with bioterrorism, crimes against humanity and conspiracy to defraud the World using Germany sponsored COVID-19 biological warfare attack.

Evidence 1/exhibit A – The overwhelming majority of COVID-19 test kits used to diagnose new COVID-19 cases in Canada, the US, the UK, the EU, Asia, Africa and throughout the World “do not detect the virus itself. Instead, they detect the antibodies produced in response to an infection … sale in Canada of serological testing devices (are) used for the detection of antibodies” Government of Canada

If serological/antibody test kits do not detect the virus that causes COVID-19 then logically and factually Canadians, Americans, British, Asian, African, and European populations are not being tested for COVID-19 and they haven’t tested positive for COVID-19.

If the tests that are used to test for COVID-19 infection don’t detect the SARS-CoV-2 virus itself they don’t and can’t be used to diagnose COVID-19 infection/new cases. That is made perfectly clear in …

Evidence 2/exhibit B – “Results from antibody testing should not be used to diagnose or exclude SARS-CoV-2 infection or to inform infection status.” stated by Johns Hopkins Medicine, the FDA, Health Canada, and product inserts for Assure, TBG, ACON,  MEGNA & BIOTIME COVID-19 IgM/IgG Antibody Rapid Test Kits

COVID-19 IgM/IgG Antibody Rapid Test Kit insert:

Evidence 3/exhibit C – “positive results for IgM and IgG antibodies may occur due to cross reactivity from pre-existing antibodies or other possible causes.

Evidence 4/exhibit D – “Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E

Screenshot of BIOTIME SARS-CoV-2 IgG/IgM Rapid Qualitative Test

ACON’s COVID-19 IgM/IgG Antibody Rapid Test Kit specifically refers to coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E as common cold strains. The CDC stated that coronavirus HKU1, NL63, OC43, or 229E usually causes mild to moderate upper-respiratory tract illnesses, like the common cold:

Common human coronaviruses, including types 229E, NL63, OC43, and HKU1, usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. Most people get infected with one or more of these viruses at some point in their lives.

CDC

Health Canada, the CDC, the WHO (agency of the UN) and Ontario Premier Doug Ford, New Brunswick Premier Blaine Higgs, Nova Scotia Premier Scotia McNeil and other governments and health authorities have all used the results from those antibody testing kits to declare a public health emergency, impose draconian measures and to justify lockdowns and travel restrictions despite the FDA, the CDC and Health Canada, etc., all stating “Results from antibody testing should not be used to diagnose or exclude SARS-CoV-2 infection or to inform infection status”

Evidence 5/exhibit E – “Most people have anti-coronavirus antibodies, reflecting universal exposure, but reinfection appears common” Johns Hopkins

COVID-19 tests detect the presence of coronavirus antibodies which Johns Hopkins has stated “Most people have anti-coronavirus antibodies”

Before Germany sponsored / funded the COVID-19 biological warfare attack (an act of war) “Acute bronchitis is one of the common presentations in any healthcare setting. It is estimated that every year, 5% of the general population reports an episode of acute bronchitis, accounting for more than 10 million office visits yearly. Like most of the viral diseases of the respiratory tract, acute bronchitis is commonly seen during the flu season. https://www.ncbi.nlm.nih.gov/books/NBK448067/

Since COVID-19 Canada, US and UK health care officials haven’t reported cases or deaths due to acute bronchitis. Why? Bill Gates & the World Economic Forum Event 201 player US RADM Stephen C. Redd is Deputy Director for Public Health Service and Implementation Science at the CDC. They’re aiding and abetting Germany and the WHO/UN stage/lead the COVID-19 biological warfare attack. They’re intentionally misleading the US, Canadian, and UK governments & the US, Canadian, UK and World population during the COVID-19 plandemic to assist Germany and the WHO steal $billions and bailout/bankroll Germany’s insolvent EU and International World Order / UN.

Germany and the WHO/UN‘s COVID-19 bioterrorism (act of bioterrorism can range from a simple hoax to the actual use of biological weapons, also referred to as biological agents) and fraud by false pretence becomes blatantly obvious when you look at the WHO data from previous years accounting/reporting of respiratory diseases. Specifically, the data from 2019.

The data below shows the WHO and it’s accomplices falsified the reporting to make it appear COVID-19 was a pandemic.

Compare WHO’s COVID-19 accounting – cases and deaths to WHO’s 2019 respiratory diseases data. When you are comparing the data keep in mind that the COVID-19 cases and deaths accounting is for 20 months (tally spans 3 calendar years 2019, 2020 and 2021) not 1 year:

“An estimated 10.0 million people fell ill with TB in 2019. An estimated 1.4 million people died from TB in 2019.” WHO Factsheet

384 million people suffer from chronic obstructive pulmonary disease (COPD) and 3 million die from it each year, making it the third leading cause of death worldwide.

1.76 million people die from lung cancer each year, making it the most deadly cancer.

4 million people die from lower respiratory tract infections and pneumonia each year.” WHO publication – The Global Impact of Respiratory Disease

Herpes virus ORF10 protein encoded in SARS-CoV-2 and in Pfizer–BioNTech and Moderna COVID-19 mRNA vaccines cause of all new cases of COVID-19

Within SARS-CoV-2 and COVID-19 mRNA vaccines is a protein called ORF10 protein. Studies have concluded that ORF10 acts as a precursor of additional RNAs in roles concerning gene expression, controlling cellular antiviral pathways, or within viral replication (Taiaroa et al., 2020). ORF10 of SARS-CoV-2 is the last predicted coding sequence upstream of the poly-A tail and is the shortest predicted coding sequence, composed of 38 a.a. (Taiaroa et al., 2020). ORF10 is predicted to harbor a long helix and a pair of ϐ-strands. ORF10 is not found within the SARS-CoV-1 proteome (Taiaroa et al., 2020). ORF10 is the only protein that is present exclusively/only in SARS-CoV-2 and not in SARS-CoV or any other human coronaviruses.

The WHO reported that the severity of COVID-19 is enhanced by the ORF10 protein. “These findings of uniqueness of ORF10 and predicted intrinsic characteristics support possible involvement of ORF10 protein in giving COVID-19 its specific characteristics like spread and virulence.” World Heath Organization

Virulence is a pathogen’s or microorganism’s ability to cause damage to a host. In most contexts virulence refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism — its ability to cause disease — is determined by its virulence factors.

These results indicate that ORF10, like its HSV-1 homolog VP16, is a transactivating protein despite the absence of sequences similar to the VP16 carboxy-terminal domain. The transactivating function of the ORF10 tegument protein may be critical for efficient initiation of viral infection.

1993 Journal of Virology published study

We conclude that ORF10 protein is required for efficient virion assembly and is a specific determinant of virulence in epidermal and dermal cells in vivo. … ORF10 protein has some, but not all, of the properties of HSV-1 VP16. … In summary, these experiments show that ORF10 protein is required for efficient viral replication, virion formation, and cell-cell spread in human.

2006 Journal of Virology published study

Nuclear export of host mRNAs is critical for proper cellular functions and survival. To mitigate this effort, viruses have evolved multiple strategies to inhibit this process. Distinct to the generally nonselective inhibition mechanisms, ORF10 from gammaherpesviruses blocks nuclear export of selective mRNAs by forming a complex with Rae1 (RNA export 1) and Nup98 (nucleoporin 98).

October 8, 2020 published research article – Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10

Viruses have evolved multiplemechanisms to inhibit cellular gene expression, thereby impeding host antiviral responses. Gong et al. identify a herpesvirus protein, ORF10, of KSHV that blocks nuclear export of selective mRNAs by interacting with an RNA export factor, Rae1. This interaction of ORF10 is critical for optimal KSHV replication.

We report that ORF10 inhibits mRNA export in a transcript-selective manner to control cellular gene expression. Nuclear export inhibition by ORF10 requires an interaction with an RNA export factor, Rae1. Genome wide analysis reveals a subset of cellular mRNAs whose nuclear export is blocked by ORF10 with the 3’UTRs of ORF10 targeted transcripts conferring sensitivity to export inhibition. The ORF10-Rae1 interaction is important for the virus to express viral genes and produce infectious virions.

2016 study “A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export

It is important to note that all viruses and virus proteins must have a unique nomenclature (name). “Consistent protein nomenclature is indispensable for communication, literature searching and entry retrieval. A good protein name is one which is unique, unambiguous, can be attributed to orthologs from other species and follows official gene nomenclature where applicable. The process of associating a name with a protein sequence has various components: sequence function identification/prediction, choosing a name and applying formatting.International Protein Nomenclature Guidelines

ORF10 protein is a protein of the human herpes virus. Herpesviruses are large DNA viruses that have two distinct life cycle phases: lytic replication and latency. During lytic replication, they operate a highly regulated viral gene expression program, resulting in the production of infectious virions. Herpesviruses are known for manipulating cellular mRNA export machinery.

The COVID-19 mRNA vaccines contain both the herpes virus protein ORF10 and instructions to make spike proteins to give the herpes virus protein ORF10 the key/means to enter cells and make us sick.

mRNA vaccines teach our cells how to make a protein—or even just a piece of a protein—that triggers an immune response inside our bodies…. COVID-19 mRNA vaccines give instructions for our cells to make what is called the spike protein.’ The spike protein is found on the surface of the virus that causes COVID-19.” CDC

Specifically, the vaccine contains the mRNA of what’s known as spike protein, which is located on the surface of the SARS-CoV-2 virus and is what it uses to invade host cells. The novel coronavirus uses spike protein like a key to gain entry to our cells; once inside, the virus is free to replicate, making us sick.” Carlos Malvestutto, MD, MPH, who specializes in infectious disease at The Ohio State University Wexner Medical Center

Germany (BioNTech vaccine) and the WHO chose to use the 2003 patented (patent US-2006257852-A1) herpes ORF10 protein encoded SARS-CoV-2 virus to ensure the novel coronavirus would reinfect (relapse) everyone who was vaccinated for years to come. There is currently no cure or preventive treatment for a herpes infection. If a person gets a herpes virus infection, they will have it for life , whether or not they experience symptoms – during the first herpes outbreak (called primary herpes), an infected person may experience flu-like symptoms. These include body aches, fever and headache.

#COVID-19, #mRNAvaccines, #vaccines, #BioNTech, #Moderna, #WHO, #SARS-CoV-2

2020 study, conducted in Sweden, found direct evidence that nitric oxide inhibits the replication of SARS-CoV-2

A 2020 study concluded that nitric oxide, a cell-signaling molecule that the body produces naturally, could be a potential treatment for COVID-19 by giving relief to patients and even containing the spread of SARS-CoV-2 coronavirus.

The study, conducted in Sweden, found direct evidence that nitric oxide inhibits the replication of SARS-CoV-2. The scientists found that nitric oxide inhibited a key enzyme called 3C-like protease (3CLpro) that the virus SARS-CoV-2 needs to make copies of itself.

The 3CL protease (3CLpro) is the main protease of the SARS-CoV-2, which is responsible for the viral replication.

“we have evaluated the in vitro antiviral effect of NO on SARS-CoV-2 replication. The NO-donor S-nitroso-N-acetylpenicillamine (SNAP) had a dose dependent inhibitory effect on SARS-CoV-2 replication, while the non S-nitrosated NAP was not active, as expected. Although the viral replication was not completely abolished (at 200 μM and 400 μM), SNAP delayed or completely prevented the development of viral cytopathic effect in treated cells, and the observed protective effect correlated with the level of inhibition of the viral replication. The capacity of the NO released from SNAP to covalently bind and inhibit SARS-CoV-2 3CL recombinant protease in vitro was also tested. The observed reduction in SARS-CoV-2 protease activity was consistent with S-nitrosation of the enzyme active site cysteine.”

“In this study, we demonstrated that NO can inhibit the replication of SARS-CoV-2 in Vero E6 and we identified the SARS-CoV-2 main protease as a target for NO. There is a great need for effective antivirals against SARS-CoV-2 to be used in the on-going COVID-19 pandemic. Based on this study and previous studies on SARS-CoV in vitro, and in a small clinical trial, we conclude that NO may be applied for clinical use in the treatment of COVID-19 and other human coronavirus infections.” research paper Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro, published October 2020

Germany and the WHO infected the World with herpes using COVID-19 mRNA vaccines

During the first herpes outbreak (called primary herpes), an infected person may experience flu-like symptoms. These include body aches, fever and headache. People who have been vaccinated with Germany’s Pfizer-BioNTech COVID-19 mRNA vaccines are experiencing the same flu-like symptoms as herpes because the human herpes virus protein ORF10 is encoded in SARS-CoV-2 and in mRNA vaccines.

There is more evidence that supports the assertion that mRNA vaccines are infecting the World population with herpes. On August 12, 2021 Europe’s drug regulator EMA published new updates on the safety of mRNA vaccines after it investigated a possible link between mRNA vaccines and a skin reaction called erythema multiforme. Erythema multiforme is a hypersensitivity reaction usually triggered by infections, most commonly herpes simplex virus (HSV).

The human herpes virus ORF10 protein (HHV-8) is the only protein that is present exclusively in SARS-CoV-2 and not in SARS-CoV or any other human coronaviruses.

The WHO’s COVID-19 Global literature on coronavirus disease suggested the severity of COVID-19 is enhanced by the human herpes virus protein ORF10.

“Could the severity of COVID-19 be enhanced by ORF10 accessory proteins?”

uniqueness of ORF10 and predicted intrinsic characteristics support possible involvement of ORF10 protein in giving COVID-19 its specific characteristics like spread and virulence

World Heath Organization

Since 1972 the WHO/UN has called for/recommended virologists develop the means to prolong virus/coronavirus infections:

An attempt should be made to see if viruses can in fact exert selective effects on immune function. e.g. by depressing (to diminish the activity, strength, or yield of) 7S (IgG) versus 19S (IgM) antibody, or by affecting T cell function as opposed to B cell function. The possibility should be looked into that the immune response to the virus itself may be impaired if the infecting virus damages, more or less selectively the cells responding to the viral antigens. If this proves to be the case, virus-induced immunodepression might conceivably be highly instrumental in prolonging certain virus infections, such as murine leukemia, hepatitis, …

Bulletin of the World Health Organization, Volume 47, p.259, 1972, Recommendations (3)

Virologists did that by genetically engineering/modifying the SARS coronavirus. The human herpes virus protein ORF10 was encoded into the SARS coronavirus to make SARS-CoV-2.

There is currently no cure or preventive treatment for the herpes infection. If a person gets either form of herpes virus infection, they will have it for life , whether or not they experience symptoms.

A 2003 patent informs us when the herpes virus protein ORF10 was added to the SARS virus by virologists to create SARS-CoV-2. The 2003 Patent US-2006257852-A1 assigned to CHIRON CORP (US), which was acquired by Novartis (Switzerland) on April 20, 2006 specifically names the ORF10 protein – a protein that is exclusively found in SARS-CoV-2 genome and not in SARS-CoV, being used/encoded in the fusion protein of the patented novel SARS coronavirus.

 

Human herpes virus protein in genome of SARS-CoV-2 provides evidence the virus that causes COVID-19 was developed for WHO to be used as a bioweapon

SARS-CoV-2 genome annotation revealed the presence of 10 open reading frames (ORFs). SARS-CoV-2 possesses two accessory proteins, ORF8 and ORF10, that share no homology to other coronavirus strains.

The SARS-CoV-2 accessory protein ORF10 (organism Human herpesvirus 8/HHV-8), a putative 38-amino acid viral protein encoded in the 3’ accessory region of the genome, is a highly ordered, hydrophobic (insoluble in water; repelling water) , and thermally stable protein, which contains at least one transmembrane region.

“the ORF10 protein contains high numbers of promiscuous cytotoxic T lymphocyte (CTL) epitopes, primarily on the α-helix. A recent study by Liu et al. 2020 found that in severe cases of COVID-19, the ORF10 was overexpressed when compared against ORF10 expression levels in moderate cases. If the ORF10 protein is synthesized (manufactured, man made), this may help to partially explain the nature behind severe cases of COVID-19. The large number of CTL epitopes in conjunction with the overproduction of the ORF10 protein could result in elevated immune responses towards SARS-CoV-2, leading to some potentially fatal immunopathological outcomes. … Alternatively, ORF10 may act itself or serve as a precursor for other RNAs in regulating gene expression/replication, translation efficiency, or interfering with cellular antiviral pathways.October 2020 study

ORF8, “although non-essential and the precise functions are unknown, it has been suggested that this protein assists in SARS-CoV-2 replication in the early secretory pathway and in immune evasion. … Since ORF8 is not an essential protein for the SARS-CoV-2 life cycle, ORF8 is likely to functionally associate with other SARS-CoV-2 components to assist with SARS-CoV-2 replication and assembly in host cells, but, the coordinated process of this mechanism is still unknown”

“It is also noteworthy that ORF10, exclusively found in SARS-CoV-2 (and not in SARS-CoV), has been shown to interact with the Cullin 2 (CUL2) RING E3 ligase complex, possibly hijacking its function. It is not known what the implications of this interaction is for virus replication, but a similar complex is recruited by other viral proteins, including HIV Vif, Adenovirus E4Orf6, EBV Bzlf and others (Mahon et al., 2014). In all cases, the virus exploits this to target an antiviral protein for proteasome degradation, and it is therefore likely the case also for Orf10.” Structural Characterization of SARS-CoV-2: Where We Are, and Where We Need to Be

Accessory proteins (ORF8, ORF10) were suggested to play an important role in virulence and host interaction in other coronaviruses (Liu et al., 2014).

Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome contains

Protein ORF10

Gene

ORF10

Organism

Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi’s sarcoma-associated herpesvirus)

Human herpesvirus 8 (HHV-8) is the infectious cause of Kaposi sarcoma (KS) and HIV-infection. HHV-8 infection is not very common in North America. It occurs more often in some Mediterranean countries and is widespread in Africa.

“In the United States, men who have sex with men (MSM) and persons with HIV infection are at increased risk for HHV-8 infection. Among MSM without HIV infection, the seroprevalence ranges from 13% to 20% and HHV-8 seroprevalence increases to 30% to 35% among MSM with HIV infection. Injection drug use may also be a risk factor for HHV-8 seropositivity, although this association has not been consistently observed.”

HHV-8 is etiologically associated with all forms of Kaposi sarcoma (KS) including classic, endemic (belonging or native to a particular people or country), transplant-related, and AIDS-related, as well as rare neoplastic disorders (primary effusion lymphoma [PEL] and solid organ variants) and the lymphoproliferative disorder known as multicentric Castleman’s disease (MCD). Although the precise pathogenesis for these tumors remains unclear, infection with HHV-8 precedes their development.” Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV

The presence of two accessory proteins, ORF8 and ORF10, that share no homology to other coronaviruses strains but appear to assist with SARS-CoV-2 replication and and in immune evasion, suggests SARS-CoV-2 was developed for the strapped for cash WHO as a bioweapon.

ORF10 protein “HHV-8 mostly causes disease mainly in immunocompromised individuals” Johns Hopkins Medicine

COVID-19 vaccines developed to assist Germany and the WHO prolong COVID-19

“The possibility should be looked into that the immune response to the virus itself may be impaired if the infecting virus damages, more or less selectively the cells responding to the viral antigens. If this proves to be the case, virus-induced immunodepression might conceivably be highly instrumental in prolonging certain virus infections, such as murine leukemia, hepatitis, … ” WHO, From the Bulletin of the World Health Organization, Volume 47, p.259, 1972, Recommendations (3)

The WHO / UN essentially directed virologists to develop ways to impair natural immune responses and prolong virus infections.

COVID-19 vaccines were developed to do just that – prolong SARS-CoV-2 infections. At least 2 vaccines were developed for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) based on a modified vaccinia virus.

“We developed two COVID-19 vaccines based on modified vaccinia virus Ankara (MVA) vectors expressing the entire SARS-CoV-2 spike (S) protein (MVA-CoV2-S)”  Spain virologist Mariano Esteban, from Madrid’s National Biotechnology Center, and by Felipe García, from the Clínic Hospital in Barcelona.

Spain’s experimental COVID-19 vaccines are based on genetic language, RNA, as are Moderna and Germany’s Pfizer-BioNtech vaccines. These vaccines introduce a genetic formula with instructions for human cells to produce the S proteins the novel coronavirus needs and uses to gain entry to our cells and once inside, the virus is free to replicate, making us sick.

The vaccinia virus “function by restricting the production of IFN by blocking the signaling pathways leading to transcription of IFN genes, stopping IFNs binding to their receptors, blocking IFN-induced signal transduction leading to expression of interferon-stimulated genes (ISGs), or inhibiting the antiviral activity of ISG products. – Geoffrey L Smith, University of Cambridge January 2018

Immunological research provides evidence that COVID-19 mRNA vaccines manufactured based on a modified vaccinia virus increases infection:

“Ferrets vaccinated with a modified vaccinia virus Ankara (MVA) vaccine expressing full-length S protein had increased infection and hepatitis following challenge71,72. Antibodies to S protein were reported to induce acute lung injury in experimentally infected macaques on the basis of histological examination.” https://www.nature.com/articles/s41577-020-00434-6

Supreme Court of Canada Justice implicated UN and WHO in targeted murders of Barry & Honey Sherman

Supreme Court of Canada (SCC) Justice presiding over a SCC case involving the unsealing of Toronto Police Services files on the double homicide investigation of Barry and Honey Sherman implicated both the UN and the WHO in the targeted murders of Barry and Honey Sherman.

The murders were a very, very sophisticated crime, in my view, committed by a very sophisticated organization – at least it has those hallmarks.Supreme Court of Canada Justice Michael Moldaver, October 6, 2020 – multiple news sources: The Chronicle Herald and the Globe and Mail

The official / legal name for the UN is the United Nations Organization. The official name for the WHO is the World Health Organization.

Why are the UN and WHO suspects in the “targeted murders” of Justin Trudeau’s August 26, 2015 election campaign fundraisers Barry and Honey Sherman? The Shermans owned Apotex which manufactured and sold Hydroxychloroquine – a cheap, effective and a less toxic metabolite of chloroquine.

In conclusion, our results show that HCQ can efficiently inhibit SARS-CoV-2 infection in vitro. In combination with its anti-inflammatory function, we predict that the drug has a good potential to combat the disease. ” research paper Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro, published March 18, 2020 – day Justin Trudeau announced the closure of Canada’s borders to most travelers during news conference outside Rideau Cottage about the measures Canada is taking to combatCOVID-19

“chloroquine is an effective pre & post-infection antiviral agent for SARS-CoV. A dose-dependant decrease in virus antigen-positive cells was observed starting at 0.1 μM chloroquine & 10 μM (Micrometre, also called micron, metric unit of measure for length equal to 0.001 mm, or about 0.000039 inch) completely abolished SARS-CoV infection. … Chloroquine, a relatively safe, effective and cheap drug used for treating many human diseases including malaria, amoebiosis and human immunodeficiency virus” Virology Journal 2005 studyChloroquine is a potent inhibitor of SARS coronavirus infection and spread“. Acknowledgements “This work was supported by a Canadian PENCE grant (T3), CIHR (Canadian Institutes of Health Research, is Canada’s federal funding agency for health research) group grant #MGC 64518, and CIHR grant #MGP-44363 (to NGS)” Virology Journal, Published 2005 Aug 22

“There is sufficient pre-clinical rationale and evidence regarding the effectiveness of chloroquine for treatment of COVID-19 as well as evidence of safety from long-time use in clinical practice for other indications.” Europe PMC paper ” A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19“.

Europe PMC is a service of the Europe PMC Funders’ Group, in partnership with the European Bioinformatics Institute ; and in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine (NCBI/NLM) .

Chloroquine was shown to inhibit in vitro replication of SARS-CoV-2 in Vero E6 cells in an effective concentration EC90 of 6.90 μM that can be easily achieved with standard dosing, due to its favourable penetration into tissues, including in the lung. This is substantially lower than the concentration detected in human plasma when the drug is prescribed to treat malaria at a dose of 25 mg/kg over 3 days. However, for COVID-19 patients, a lower dose such as 3.6 mg/kg that are often prescribed to treat rheumatoid arthritis has been suggested for long-term patients as the dose is similar to IC50 for SARS-CoV. It is to be noted that hydroxychloroquine (made by Justin Trudeau’s August 26, 2015 election campaign fundraisers Barry and Honey Sherman who were targeted and murdered December 13, 2017 – 7 days before Justin Trudeau was convicted of violating federal ethics laws) showed greater efficacy than chloroquine, at least based on in vitro studies. Besides, hydroxychloroquine was shown to have minimal risk of toxicity such as retinopathy. Other recent studies also showed that hydroxychloroquine is a less toxic metabolite of chloroquine, as it is more soluble, and causes less side effects and therefore is safer. … both hydroxychloroquine and chloroquine can interfere with ACE2 receptor glycosylation and prevents SARS-CoV-2 binding to pneumocytes. Chloroquine could also possibly inhibit sialic acid biosynthesis thus limiting cell surface binding of SARS-CoV-2.

Biological Trace Element Research (2021) 199:550–558

Barry Sherman’s Apotex drug Hydroxychloroquine clearly threatened to prematurely end Germany and WHO’s COVID-19 biological warfare attack and defund the bankrupt / insolvent UN / WHO & Bill Gates’ lucrative multi $billion global vaccine agenda.

The Barry & Honey Sherman murders in 2017, coincided with Germany and the WHO initiating their planning and preparing for the COVID-19 biological attack.

The WHO and Germany initiated the COVID-19 plandemic during the G20 Germany 2017 summit. “By putting global health on the agenda of the G20, we affirm our role in strengthening the political support for existing initiatives and working to address the economic aspects of global health issues. We support the leading role of the World Health Organization (WHO), as the United Nations specialized agency for health, in global health cooperation. Furthermore, we seek to intensify global action and cooperation in order to address ever-evolving challenges and identify where the health sector can provide leadership and added value…. We conducted a simulation exercise during our meeting in Berlin in May 2017 in close cooperation with the World Health Organization (WHO), … The international community needs to fully support the WHO in order for the organization to be able to fulfill its role, including in capacity building and in preparing for and responding to health emergencies. In this respect, we acknowledge that WHO’s financial and human resource capacities have to be strengthened, including through adequate and sustainable funding for the Health Emergencies Programme and the WHO Contingency Fund for Emergencies (CFE).” Berlin Declaration of the G20 Health Ministers